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Risk factors for Intensive Care admission of children with severe acute wheeze or asthma

Completed
Conditions
life-threatening asthma attack
Status Asthmaticus
10006436
Registration Number
NL-OMON44930
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
220
Inclusion Criteria

-Between 2 and 18 years of age
-Admission to a PICU for status asthmaticus or acute wheeze
-Admission to a MC for status asthmaticus or acute wheeze

Exclusion Criteria

-Patient is outside of specified age range
-Patient has Down*s Syndrome
-Patient has a congenital/acquired heart defect that interferes with normal SAA treatment
-Patient has a congenital/acquired airway defect (Tracheomalacia, Bronchomalacia)
-Patient has a primary/secondary immunodeficiency
-Patient has a pre-existing chronic pulmonary condition, known to mimic asthma: Cystic fibrosis, Bronchopulmonary dysplasia, Bronchiolitis obliterans.
-Any subject who receives a different diagnosis than SAA / asthma exacerbation within the timeframe of the admission
-Any subject who does not provide informed consent or repeals informed consent (either by patient or by guardian(s)).

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Undertreatment, defined as:<br /><br>Patient is not using inhaled corticosteroids (ICS), or<br /><br>Patient is using ICS for <7 days (counting from moment of admission to<br /><br>emergency department) according to treatment plan, or<br /><br>Patient is not using ICS according to treatment plan.<br /><br><br /><br>Use of medication is estimated through obtaining pharmacy records on medication<br /><br>that was picked up by the patient, versus the medication that is required<br /><br>according to the treatment plan. If a patient indicates that he/she did not use<br /><br>their medication correctly (despite pharmacy records indicating pickup), this<br /><br>patient is counted as being undertreated.</p><br>
Secondary Outcome Measures
NameTimeMethod
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