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Clinical Trials/NCT05094986
NCT05094986
Completed
N/A

Pilot of a Complex Intervention to Improve Initial Medication Adherence to Cardiovascular and Diabetes Treatments in Primary Care

Fundació Sant Joan de Déu5 sites in 1 country605 target enrollmentNovember 1, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Adherence, Medication
Sponsor
Fundació Sant Joan de Déu
Enrollment
605
Locations
5
Primary Endpoint
Rate of clinical registries related to diabetes mellitus II
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This pilot study aims to test the feasibility of the following effectiveness and cost-effectiveness evaluation using Real-World Data.

Detailed Description

A cluster non-randomised pilot study with an embedded process evaluation was carried out to test the feasibility of the definitive cluster randomised controlled trial (cRCT). The cRCT will aim to evaluate the effectiveness and cost-effectiveness of the Initial Medication Adherence (IMA) intervention in comparison to usual care, to increase initiation of pharmacological treatments for CVD and diabetes (antihypertensive drugs, hypolipidemic drugs, antiplatelet drugs, and insulin and oral antidiabetics) prescribed in Primary Care (PC). The pilot study was conducted in five PC centres (PCC) in Catalonia (Spain), two were assigned to the control group and three to the intervention group. There were two target participants, the implementation targeted professionals (general practitioners (GP), nurses, and community pharmacists), and the population targeted by the intervention, PC patients. The IMA intervention provided healthcare professionals with the knowledge, skills, and tools to help the patient make an informed and shared decision with the GP to initiate a new CVD or diabetes treatment. Professionals were trained on the problem of non-initiation, communication skills, health literacy, and the use of decision aids (leaflets, website).

Registry
clinicaltrials.gov
Start Date
November 1, 2020
End Date
June 30, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Maria Rubio-Valera

Head of Quality and Patient Safety

Fundació Sant Joan de Déu

Eligibility Criteria

Inclusion Criteria

  • Primary healthcare professionals and pharmacists who:
  • Agree to participate in the pilot study.
  • Primary care patients who:
  • Are prescribed a new treatment of cardiovascular disease o diabetes by a GP who participates in the clinical trial.
  • Are \>18 years old.
  • Do not reject to participate.

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Rate of clinical registries related to diabetes mellitus II

Time Frame: 5 months before and after recruitment

Rate of registries recorded five months before and after the prescription of: * Glycated haemoglobin * Glomerular filtrate * Blood glucose

Rate of clinical registries related to cardiovascular risk

Time Frame: 5 months before and after recruitment

Rate of registries recorded five months before and after the prescription of: • REGICOR

Rate of clinical registries related to dyslipidemia

Time Frame: 5 months before and after recruitment

Rate of registries recorded five months before and after the prescription of: * Total colesterol * HDL cholesterol * LDL colesterol

Rate of clinical registries related to hypertension

Time Frame: 2 months before and after recruitment

Rate of registries recorded one to two months before and after the prescription of: * Systolic blood pressure * Diastolic blood pressure

Rate of use of services

Time Frame: 5 months before and after recruitment

Rate of use of services recorded five months before and after the prescription of: * Visits to primary care (nurse, GP) * Referrals to secondary care * Productivity losses (sick leave days) * Outpatient diagnostic tests

Secondary Outcomes

  • Outliers registries(5 months before and after recruitment)
  • Missing registries(5 months before and after recruitment)
  • Active diagnosis registry(5 months before and after recruitment)

Study Sites (5)

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