NOMAC : New Tools for Managing the Fate of Cereal Nutrients in the Gut : Effects of Amylose Content on Glycemic Index.

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: 20% amylose bread; Dietary Supplement: 10% amylose bread; Dietary Supplement: Carbohydrates

• Registration Number: NCT01437917
• Lead Sponsor: Rennes University Hospital

Brief Summary

The consumption of cereals-based foods with low glycemic indexes, high micronutrients and fibers contents are highly recommended. The target of this work is to provide new solutions for cereal based foods: the knowledge and understanding on the in vivo fate will be used to define structural features to gain in foods.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-09
• Study First Submitted: 2011-09-20
• Study First Submitted QC: 2011-09-20
• Study First Posted: 2011-09-21
• Primary Completion: 2012-04
• Study Completion: 2012-04
• Status Verified: 2012-05
• Last Update Submitted: 2012-05-15
• Last Update Posted: 2012-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Healthy individual,
• Age between 19-65 years
• With normal food habits with at least 2 main meals per day
• Non smoking
• Having filled the consent form

Exclusion Criteria

• BMI > 25 kg/m2,
• Diabetes or any illness susceptible to alter
• Coeliac disease
• Past history of intestinal diseases.
• Treatment susceptible of modifying glycemia.
• Allergy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Bread with 20% amylose content	20% amylose bread	Bread with 20% amylose content
Bread with 10% amylose content	10% amylose bread	Bread with 10% amylose content
carbohydrates	Carbohydrates	50g of carbohydrates ingested with 400 ml of water

Primary Outcome Measures

Name	Time	Method
Glycemic index for each bread	2 hours	To compare the glycemic index of breads made with different amylose content. (S1 to S6) A total of 6 visits. In each visit, blood samples will be taken for measurement of glycemia and insulinemia over 2 hours after ingestion of 50 of carbohydrates ingested with 400 ml of water.

Secondary Outcome Measures

Name	Time	Method
AUC for insulinemia for the 2 hours following the ingestion of each bread.	2 hours	To compare the AUC for insulinemia for the 2 hours following the ingestion of each bread.

Trial Locations

Locations (1)

Rennes University Hospital; 🇫🇷 Rennes, Bretagne, France