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Clinical Trials/NCT07310966
NCT07310966
Not yet recruiting
Not Applicable

Comparison of Lithotomy Versus Lateral Position in Retrograde Intrarenal Surgery for Lower Calyceal Stones Less Than 2 cm: A Randomized Controlled Trial

Menoufia University1 site in 1 country70 target enrollmentStarted: January 1, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
70
Locations
1
Primary Endpoint
Stone Free Rate

Overview

Brief Summary

Retrograde intrarenal surgery (RIRS) is an established minimally invasive treatment for renal stones, particularly for lower calyceal stones less than 2 cm, offering acceptable stone-free rates with low morbidity.

However, stone clearance in the lower calyx remains technically challenging due to unfavorable anatomy, limited scope deflection, and gravity-dependent fragment retention. Patient positioning during RIRS has been suggested as a modifiable factor that may influence endoscopic access, stone relocation, and surgical ergonomics.

The lithotomy position is conventionally used during RIRS, while the lateral position has been proposed to facilitate stone migration and improve lower calyceal access through gravitational assistance. Existing studies comparing patient positioning during RIRS are limited, with most evidence derived from retrospective analyses or non-randomized designs.

Therefore, this randomized controlled trial aims to compare lithotomy versus lateral positioning during RIRS for lower calyceal stones less than 2 cm in terms of operative and clinical outcomes.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Adults aged ≥18 years.
  • Single or multiple lower calyceal renal stones with stone size \<2 cm confirmed by NCCT.
  • Negative urine culture.
  • Presented cases.

Exclusion Criteria

  • Multiple stones involving renal pelvis or other calyces.
  • Anatomical anomalies affecting ureteroscope access (horseshoe kidney, malrotation, ureteral strictures).
  • Pregnancy.
  • Prior ipsilateral renal surgery.

Outcomes

Primary Outcomes

Stone Free Rate

Time Frame: 1 month

Stone-free rate (SFR), defined as no clinically significant residual stones on non-contrast 3-mm-cuts CT, measured as yes or no

Secondary Outcomes

  • Operative time(The operative time)
  • Complications(1 month)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ammar Fathi Mohamed AlOrabi

Dr

Menoufia University

Study Sites (1)

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