Donor Gender Effect on Graft Function in Adult Egyptian Patients Undergoing Living Donor Liver Transplant
Completed
- Conditions
- Donor to Recipient Gender Mismatch in LDLT
- Interventions
- Other: non interventional
- Registration Number
- NCT04068363
- Lead Sponsor
- Ain Shams University
- Brief Summary
Liver transplantation (LT) represents the gold-standard therapy for the treatment in case of dreadful liver pathologies . It is thus a main concern to optimize the results in terms of post-LT survivals. The effect of gender match on post-transplant outcome is still debatable. Hormonal , and size difference between female and male may be proposed to affect the post transplant outcome . The aim of this study is to evaluate the effect of donor-recipient gender mismatch on survival rates
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 342
Inclusion Criteria
- Adult Egyptian Patients >18 years.
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Exclusion Criteria
- Patient refusal.
- Patients who underwent re-transplantation before discharge from the ICU after the first liver transplant.
- Intraoperative cardiac arrest or immediately postoperative cardiac arrest within the first 6 hours postoperative.
- Massive blood loss.
- Pre-existing renal failure requiring hemodialysis or continuous hemofiltration.
- Pregnancy.
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Mismatched group non interventional Sex mismatch between donor and recipient, subgroups might be added Matched group non interventional Same sex of both donor and recipient
- Primary Outcome Measures
Name Time Method 2 years survival post liver transplant. 3 months The primary outcome will be survival at 2 years post liver transplant
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hanaa El Gendy
🇪🇬Cairo, Ain Shams University Specialized Hospital, Egypt