NCT02070575CompletedNot Applicable
Evaluation of Molecular Forms of PSA and Human Kallikrein 2 in a Cohort of Patients With Locally Resected Prostate Cancer But Biochemical Recurrence
Memorial Sloan Kettering Cancer Center1 site in 1 country200 target enrollmentStarted: February 20, 2014Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- profile of a panel of kallikrein related serine proteases in the blood
Study Overview
Brief Summary
The purpose of this study is to investigate if a new blood test looking at PSA and a group of PSA related proteins in a patient's blood can indicate which men after surgery with a rising PSA could benefit from treatment, and/or indicate which men are at higher risk for recurrence before initial treatment is given.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 30 Years to — (Adult, Older Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •All patients treated with radical prostatectomy that develop a rising serum PSA ≥ 0.05ng/ml and have not received any kind of additional therapy.
- •Patients who have had additional therapy post radical prostatectomy are eligible for this study if ≥1 year has passed since treatment and the patient develops a rising serum PSA ≥0.05ng/ml.
Exclusion Criteria
- •Previous additional therapy for prostate cancer, less than 1 year ago
- •No evidence of rising PSA
- •Patients unwilling to undergo venesection
Outcomes
Primary Outcomes
profile of a panel of kallikrein related serine proteases in the blood
Time Frame: 2 years
of patients that present with biochemical recurrence after radical prostatectomy.
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Recruiting
Not Applicable
Determination of Prostate-specific Antigen in Capillary Blood (PSA-Cap)Prostate CancerNCT06626386Heinrich-Heine University, Duesseldorf200
Recruiting
Not Applicable
PSA Glycomics Assay for Early Detection of Prostate CancerPSAProstate CancerNCT04393376Prof.dr. H.P. Beerlage150
Completed
Not Applicable
Test Semiquantitative Prostate Specific Antigen (PSA)Prostatic DiseasesProstate CancerProstatic NeoplasmsNCT00853710Institut Curie94
Not yet recruiting
Not Applicable
Examination of SASP relted compounds in human bloodife style related diseaseJPRN-UMIN000011108kyoto univ. hsp.60
Completed
Not Applicable
Analytical Validation of the abioSCOPE Device With the IVD CAPSULE PSP Test: Comparison of PSP Values Measured With Venous Whole Blood and Those Measured With Arterial Whole Blood.Sepsis BacterialSepsisNCT05627076Abionic SA46