NCT01310361已完成1 期
Once-daily Therapy for Streptococcal Pharyngitis
Azad University of Medical Sciences1 个研究点 分布在 1 个国家开始时间: 2004年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 试验地点
- 1
研究概览
简要总结
In some studies once daily amoxicillin therapy might be treatment of choice for Group A β-hemolytic Streptococcus pharyngitis in comparison with three to four times daily treatment with oral penicillin V.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Years 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inclusion Criteria:
- •Age of 6 to 15 years old.
- •The criteria in clinical examination including objective signs (fever, Erythema or exudate of tonsils, enlarged lymph nodes) and subjective sign(sore throat). Neck tenderness, abdominal pain and pharynx petechia were also considered.
- •No antibiotic was used during the week before.
- •Performing throat culture before the initiation of drug administration
- •Positive throat culture indication GABHS
- •No previous history of allergy to penicillin .
排除标准
- •Age of below 6 years old or above 15 years old.
- •No signs of pharyngitis in the clinical examination
- •Antibiotic use during the week before.
- •Throat culture was not performed before the initiation of drug administration.
- •Negative throat culture or the culture indicates a microorganism other than GABHS.
- •History of allergy to penicillin
- •Not using drugs or not following the treatment in the field of having the second culture performed.
研究组 & 干预措施
Amoxicillin
Experimental
Once-daily Therapy for Streptococcal Pharyngitis With Amoxicillin
干预措施: Amoxicillin (Drug)
Benzathin Penicillin G
Active Comparator
Once-daily Therapy for Streptococcal Pharyngitis With Intramuscular Benzathin Penicillin G
干预措施: Intramuscular Benzathin Penicillin G (Drug)
研究者
研究点 (1)
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