etrozole for IUI
Phase 2
Recruiting
- Conditions
- Female Infertility.Female infertility
- Registration Number
- IRCT20220412054511N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
Have a history of at least one year of infertility
Absence of underlying disease including abnormal thyroid stimulating hormone prolactin
Spermogram within acceptable range for IUI
At least one fallopian tube is open.
Exclusion Criteria
History of allergy to letrozole and other aromatase inhibitors
History of allergy to cabergoline and other ergot derivatives
History of pelvic surgery
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ovarian response (the number of follicle with size more than 14 millimeter). Timepoint: The day 9 to 11 of menstruation cycle. Method of measurement: Vaginal ultrasound.;Ovarian response (the size of biggest follicle). Timepoint: The day 9 to 11 of menstruation cycle. Method of measurement: Vaginal ultrasound.;Endometrial thickness. Timepoint: The day 9 to 11 of menstruation cycle. Method of measurement: Vaginal ultrasound.;The number of HMG ampoules required. Timepoint: from day 11 to 13 menstruation cycle. Method of measurement: Medical record.
- Secondary Outcome Measures
Name Time Method Pregnancy (Positive BHCG test). Timepoint: Two weeks after IUI (intra uterine insemination). Method of measurement: Blood test.;Abortion. Timepoint: During 3 months after pregnancy confirmation. Method of measurement: Getting out of pregnancy products (direct observation or ultrasound).