CTRI/2026/04/108179
Not yet recruiting
Not Applicable
To Evaluate the Efficacy of Bone Marrow Derived Mononuclear Stem Cells Combined with Platelet Rich Plasma Seeded into Allogenic Bone Graft in Alveolar Bone Grafting in cleft patients – A Novel Revolutionary Technique
Not provided0 sites30 target enrollmentStarted: April 30, 2026Last updated:
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 30
Overview
Brief Summary
The aim of this study is to assess the bone regenerative ability of autologous bone marrow derived mononuclear stem cells in combination with Platelet Rich Plasma seeded into allogenic bone graft in Alveolar bone grafting HYPOTHESIS - Autologous Bonoemarrow mononuclear stem cells in combination with platelet rich plasma seeded into Allogenic bone graft acts as osteogenic graft in promoting superior bone regeneration in alveolar bone grafting and this technique can be considered as an alternative for iliac bone harvesting
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- None
Eligibility Criteria
- Ages
- 5.00 Year(s) to 15.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients born with alveolar defects including cleft lip and palate Patients age range 5-15years Non syndromic patients Non infectious patients Patients willing to be part of the study.
Exclusion Criteria
- •Patients who underwent previous SABG procedure Syndromic patient Patients with uncontrolled systemic diseases Immunocompromised or immune suppressed patients Patients with Cardiac abnormalities Hematologic diseases Paget’s disease Osteopetrosis Rickets Any other Bony pathological conditions neoplastic condition Chemotherapy.
Investigators
Acchuthaubanyashri
Meenakshi Ammal Dental College And Hospital
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