Some Biomarkers Underlying in Ischemic Stroke in Chinese Young Adults: a Protocol for a Case-control Clinical Trial
Overview
- Phase
- Not Applicable
- Sponsor
- Beijing Chao Yang Hospital
- Enrollment
- 200
- Primary Endpoint
- the incidence of Ischemic Stroke in Chinese Young Adults
Overview
Brief Summary
Stroke is the fifth leading cause of death in the United States and the leading cause of disability. However, in China, stroke is one of the most frequent causes of death and chronic disability. Ischemic strokes in adults younger than 45 years of age were regarded as a relatively uncommon event in the proportion of <5% of all ischemic strokes.
Detailed Description
Currently, stroke is the fifth leading cause of death in the United States and the leading cause of disability. However, in China, stroke is one of the most frequent causes of death and chronic disability. Ischemic strokes in adults younger than 45 years of age were regarded as a relatively uncommon event in the proportion of <5% of all ischemic strokes. Our study aimed to evaluate some Biomarkers Underlying in Ischemic Stroke in Chinese Young Adults.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to 45 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patients between 18 and 45 years of age with a first ever ischaemic stroke are eligible for this study from the Department of Beijing Chaoyang Hospital between January 1, 2016 and December 31,
- •All patients were defined as a sudden loss of global or focal cerebral function that persisted with a probable vascular cause for 24h and confirmed by brain CT or MRI.
Exclusion Criteria
- •The exclusion criteria will include patients with intracranial lesions or cerebrovascular disease (including cerebral venous sinus thrombosis)
- •History that have caused sequelae, such as movement disorders, mood disorders, cognitive dysfunction or speech problems; or individuals who are pregnant or breast feeding.
- •Patients with serious diseases that are related to the heart, liver, kidney or haematopoietic system will not be allowed to participate.
Outcomes
Primary Outcomes
the incidence of Ischemic Stroke in Chinese Young Adults
Time Frame: every two months, up to 24 months
the incidence of Ischemic Stroke
Secondary Outcomes
No secondary outcomes reported
Investigators
Guang Wang
Director, Head of Endocrinology, Principal Investigator
Beijing Chao Yang Hospital