Uterine Peristalsis in IVF

Not yet recruiting

• Conditions: Infertility, Female

• Registration Number: NCT06036459
• Lead Sponsor: Assiut University

Brief Summary

An observational prospective cohort study to evaluate the effect of uterine peristalsis at the time of embryo transfer on IVF clinical outcomes performed in Women's Health hospital, Assiut University, Egypt.

Women performing fresh or frozen embryo transfer who do not have any uterine abnormalities will be included in the study

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-13
• Status Verified: 2023-09
• Study First Submitted QC: 2023-09-12
• Study First Posted: 2023-09-14
• Last Update Submitted: 2023-09-18
• Last Update Posted: 2023-09-21
• Study Start: 2023-10
• Primary Completion: 2025-10
• Study Completion: 2026-06

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 117

Inclusion Criteria

• • Women undergoing embryo transfer during IVF cycles.

  • Age: between 20 and 40 years.
  • Have at least 1 good quality embryo at the time of transfer
  • Fresh or frozen-thawed cycles.
  • Any stimulation protocol in fresh cycles, or any endometrial preparation protocol for frozen-thawed cycles

Exclusion Criteria

• • Women refusing to participate in clinical research.

  • Any uncorrected uterine abnormality, such as septum, myoma, adenomyosis, or polyp
  • Hydrosalpinx without prior disconnection or excision

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy	2 weeks after a positive pregnancy test	The presence of intrauterine gestational sac and fetal pole with positive cardiac pulsation by transvaginal ultrasound

Secondary Outcome Measures

Name	Time	Method
Biochemical pregnancy	2 weeks after embryo transfer	a positive serum human chorionic gonadotropin
Miscarriage	From 6 weeks of gestation until 28 weeks of gestation	Pregnancy loss either loss of cardiac pulsation by ultrasound, or spontaneous loss of pregnancy vaginally
Ongoing pregnancy	After 12 weeks of gestation until delivery	The presence of a viable pregnancy after 12 weeks of gestation
Live birth	From 28 weeks of gestation until delivery	Delivery of a living foetus after the age of viability
Ectopic pregnancy	the site of the gestational sac will be assessed 2 weeks after embryo transfer	Pregnancy outside the uterine cavity