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Clinical Trials/NCT00960817
NCT00960817
Unknown
Early Phase 1

"Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up

Hillel Yaffe Medical Center1 site in 1 countryAugust 18, 2009

Overview

Phase
Early Phase 1
Intervention
Statin, aspirin
Conditions
Coronary Angiography
Sponsor
Hillel Yaffe Medical Center
Locations
1
Primary Endpoint
Alleviation of chest pain
Last Updated
16 years ago

Overview

Brief Summary

The investigators will investigate patients undergoing coronary angiography with normal coronary but slow blood flow that was normalized after adenosine injection into the coronary artery. The investigators believe that they have small vessel coronary disease which is the initial presentation of coronary disease prior to anatomical narrowing. To alleviate this phenomenon the investigators intend to examine the long-term clinical response of these patients to treatment with dipyridamole, a well-known medication with almost no side-effects that increases the level of adenosine in the tissue.

Registry
clinicaltrials.gov
Start Date
August 18, 2009
End Date
TBD
Last Updated
16 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Patients undergoing coronary angiography and who have normal coronary artery with slow blood flow that normalized with adenosine injection into the coronary artery

Exclusion Criteria

  • Significant coronary disease
  • Unstable patients
  • Patients with known sensitivity to dipyridamole

Arms & Interventions

1. Routine treatment

Control group

Intervention: Statin, aspirin

2. Dipyridamole treatment

Group that receives Dipyridamole treatment

Intervention: Dipyridamole

Outcomes

Primary Outcomes

Alleviation of chest pain

Time Frame: Two years

Study Sites (1)

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