Baskent University Nephrology Department
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 169
- 主要终点
- Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients
研究概览
简要总结
The aim of the study is to investigate the factors influencing hemoglobin variability with inflammatory and nutritional parameters and its associations with all-cause mortality among hemodialysis patients.
详细描述
Fluctuation in hemoglobin levels that is known as hemoglobin variability during treatment with ESA is a well-documented phenomenon. Several factors have been found to affect hemoglobin variability, including drug related, such as pharmacokinetic parameters, patient-related differences in demographic characteristics and factors affecting clinical status, as well as clinical practice guidelines, treatment protocols and reimbursement policies. Inflammation is also an important factor associated with hemoglobin variability, and the consequences of persistent inflammatory activity are far-reaching in affected patients.
In present study, the factors influencing hemoglobin variability with inflammatory and nutritional parameters and its associations with all-cause mortality among hemodialysis patients are investigated.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •on chronic hemodialysis treatment
排除标准
- •All patients had a minimum of six hemoglobin measurements within a 6- month period, and they were excluded if they received a kidney transplant during this period or those who had blood transfusions during the baseline period.
- •Patients with serum ferritin<100 μg/L were also excluded from the study because of reimbursement of our country.
结局指标
主要结局
Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients
时间窗: six month
investigation of factors influencing hemoglobin variability with inflammatory and nutritional parameters and the association of hemoglobin variability with all-cause mortality among hemodialysis patients
次要结局
未报告次要终点
研究者
Zeynep Bal
Baskent University Nephrology Department
Baskent University