ACTRN12614000630617进行中(未招募)未知
A single centre, randomised, unblinded, prospective trial on the diagnostic performance and cost of coronary computed tomographic angiography compared to exercise stress angiography in patients presenting to the emergency department with chest pain suspected of acute coronary syndrome.
Queensland Emergency Medicine Research Foundation0 个研究点目标入组 592 人开始时间: 2014年6月13日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 592
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Diagnosis
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 30 Years 至 85 Years(—)
- 性别
- All
入选标准
- •Males greater or equal to 30 and females greater or equal to 40 years of age presenting to the ED with acute undifferentiated chest pain were eligible for inclusion in the trial. Inclusion criteria included intermediate probability of coronary artery disease according to the Cardiac Society of Australia and New Zealand guidelines; initial 12-lead ECG without evidence of acute ischemia, TIMI (Thrombolysis in Myocardial Infarction) risk score <4 and a negative first serum sensitive troponin-I with a 99th centile at <0.04 ng/ml (Access 2 immunoassay, Beckman-Coulter)
排除标准
- •Exclusion criteria were previous diagnosis of coronary artery disease; confirmed pregnancy or lactating female; history of severe reactive airway disease or current exacerbation; allergy or contraindication to iodinated contrast or beta-blockade medications; current atrial fibrillation; renal impairment (eGFR < 50ml/minute using the MDRD equation). To be eligible for randomization, subjects needed to be pain-free and potentially able to exercise on a treadmill.
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