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Clinical study to evaluate the safety and efficacy of Safuf Bara? in Bara? (Vitiligo)

Phase 2
Conditions
Health Condition 1: L80- Vitiligo
Registration Number
CTRI/2024/04/065215
Lead Sponsor
ATIONAL RESEARCH INSTITUTE OF UNANI MEDICINE FOR SKIN DISORDERS
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

The following patients will be included in the study:

1.Patients of any sex aged 18-60 years

2.Non-Segmental Vitiligo with Chronicity of 6

months to 2 years

3.Vitiligo involving more than 2% Body Surface Area (BSA)

4.Patients with less than 5 New Lesions in the last month

5.Patients with less than 15 lesions in the last 3 months

6.Patients who have not received systemic treatment within 4 weeks prior to study entry

7.Patients who have not received topical

treatment within 2 weeks prior to study entry

Exclusion Criteria

The following patients will be excluded: 1.Patients aged less than 18 years or more than 60 years

2. Segmental Vitiligo/ Lip-Tip Vitiligo/ Universal Vitiligo/ Vitiligo with Leucotrichia

3. Significant Pulmonary/ Cardiovascular/ Hepatorenal Dysfunction, and other Disorders requiring long-term treatment

4. Known cases of Immunocompromised states (HIV/ AIDS, etc.)/ Malignancies

5. Pregnant or Lactating Women Patient not willing to attend treatment schedule regularly

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Reduction in Vitiligo Area Scoring Index (VASI) <br/ ><br>Timepoint: 0,2,4 and 8 weeks
Secondary Outcome Measures
NameTimeMethod
1. Vitiligo Impact Scale-22 (VIS- <br/ ><br>(Assessment of Patient’s Quality of Life) <br/ ><br>2. Improvement in Patient’s Global Assessment (PGA) on VAS <br/ ><br>3. Improvement in Investigators Global Assessment (IGA)Timepoint: 0 and 8 weeks
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