Tranexamic Acid (drug)in Liver Cirrhosis (liver disease).
- Conditions
- Health Condition 1: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2020/08/027379
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients greater than 18 years of age
2.Presenting with Acute UGI bleed (less than 24 hrs from onset)
3.Cirrhosis (Known Or suspected on clinical, biological, radiological data or the patient history) with CTP B or C (i.e. CTP greater than equals to 7) or ACLF (with clinical evidence of cirrhosis)
1.Non cirrhotic patients
2.Known allergy to Tranexamic Acid
3.Patients with clinical evidence of DIC (Disseminated Intravascular Coagulation) like
coagulopathy patches/ haematuria / uncontrolled epistaxis etc.
4.Patients with Chronic Kidney Disease.
5.History of recent Cerebro Vascular Accident (CVA) [in the past 6 months] or patients with thrombotic events [Portal Vein thrombosis /Hepatic vein thrombosis /other sites thrombosis]. HCC with tumour thrombosis will be included
6.Any history of seizures, myocardial infarction
7.Pregnancy/lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method