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临床试验/CTRI/2026/01/100687
CTRI/2026/01/100687尚未招募4 期

Comparative study between the use of ultrasound guided diaphragmatic excursion ratio versus the ventilator criteria from weaning in mechanically ventilated patients in ICU.

Smt Bhikiben Kanjibhai Shah Medical Institute and Research Centre1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年1月16日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
This study will help us in weaning off in ICU based on usg criteria vs ventilator criteria

研究概览

简要总结

AIM

The timing of weaning should be carefully considered to prevent adverse effects. Our goal is to look at the predictive values of DTF and DE in terms of extubation rate and to decide when the patient should be extubated for successful weaning in mechanically ventilated patients in ICU.

OBJECTIVES

  1. To assess accuracy of USG based criteria in predicting success of weaning off from mechanical ventilation.

  2. To compare accuracy of USG based criteria vs ventilator criteria in predicting success of weaning off from mechanical ventilation.

INCLUSION CRITERIA

  1. Patients whose relatives are willing to sign informed consent

  2. Male or Female patients more than 18 years of age.

  3. Respiratory failure requiring mechanical ventilation for more than 24 h

  4. Meeting all of the following criteria for the SBT: FiO2<50%, positive end-expiratory pressure ≤5 cmH2O, respiratory rate≤30 breaths/min, PaO2/FiO2>200 mmHg

  5. hemodynamic stability in the absence of vasopressors.

EXCLUSION CRITERIA

  1. Patient with neuromuscular disease and tracheostomy.

  2. Patients with diaphragm paralysis on either side were excluded.

  3. Patient with spinal cord injury higher than T8.

  4. Patient with arrhythmias and pregnancy were excluded.

Site of Study: Department of anaesthesiology, Dhiraj Hospital, S.B.K.S.Medical Institute and research Centre, Piparia, Waghodia, Vadodara

Study Design: Prospective c o m p a r a t i v e study

Study Duration: The study will be initiated after obtaining permission from institutional ethics committee till the achievement of the sample size or by whichever is earlier.

Outcome of study - This prospective study will help us to compare the efficacy of USG based criteria vs ventilator criteria in predicting success of weaning off IN MECHANICALLY VENTILATED PATIENTS IN ICU.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Patients whose relatives are willing to sign informed consent Male or Female patients more than 18 years of age Respiratory failure requiring mechanical ventilation for more than 24 h Meeting all of the following criteria for the SBT FiO2 less than 50% positive end-expiratory pressure less than or eqal to 5 cmH2O respiratory rate less than or equal to 30 breaths/min PaO2 FiO2 ration more than 200 mmHg hemodynamic stability in the absence of vasopressors.

排除标准

  • Patient with neuromuscular disease and tracheostomy Patients with diaphragm paralysis on either side were excluded Patient with spinal cord injury higher than T8 Patient with arrhythmias and pregnancy were excluded.

结局指标

主要结局

This study will help us in weaning off in ICU based on usg criteria vs ventilator criteria

时间窗: Before extubation

次要结局

  • To compare accuracy of USG based criteria vs ventilator criteria in predicting success of weaning off from mechanical ventilation(48 hours)

研究者

发起方
Smt Bhikiben Kanjibhai Shah Medical Institute and Research Centre
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Saloni Shah

Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre

研究点 (1)

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