NL-OMON33283
Recruiting
Phase 4
Evaluation of cognitive function of patients treated with sunitinib or sorafenib (UMCONCO200904 - Evaluation of cognitive function of patients with sunitinib or sorafenib
niversitair Medisch Centrum Sint Radboud0 sites80 target enrollmentTBD
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- GIST
- Sponsor
- niversitair Medisch Centrum Sint Radboud
- Enrollment
- 80
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\-patients with metastastic renal cell cancer or GIST who are on treatment with Sunitinib or
- •Sorafenib for \>\= 8 weeks
- •\- Karnofsky score \> 70%
- •\- age \> 18 year.
- •\- written informed consent for study;Healthy controls selection:
- •\-Healthy individuals:
- •\- Karnofsky score \> 70%
- •\- age \> 18 year
- •\- written informed consent for study;Patient controls selection
- •\-patients with metastastic renal cell cancer or GIST who aren\*t treated yet (only interferon alfa or interleukine 2 treatment is allowed when \> 12 months ago.
Exclusion Criteria
- •\- contra\-indications for treatment with Sunitinib or Sorafenib
- •\- patients who do not speak or write the Dutch language adequately
- •\- known brain metastasis
- •\- use of psychiatric or anti\-epileptic medication
- •\- known cognitive disorders unrelated to diagnosis or medication use
- •\- radiotherapy on the brain at any time in the past
- •\- systemic chemotherapy
- •\- in the last 12 months interferon alfa or interleukine\-2 treatment
- •\- operation in the last 6 months
- •\- Diabetes Mellitus
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Assessment of cognitive functions in patients with alcohol-dependenceHealth Condition 1: G- Mental HealthCTRI/2021/12/039034Indian Council of Medical Research Delhi
Unknown
Phase 3
Assessment of Cognitive Function in patients with extracranial and intracranial stenosisNervous System DiseasesPACTR201911798073249Ain Shams University Hospitals30
Completed
Not Applicable
The evaluation of the cognitive function in patients with fracture and the effect of rehabilitation on cerebral functioFemoral fracture, Spinal compression fractureJPRN-UMIN000016406Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University50
Recruiting
Not Applicable
An observational study for patients with cognitive impairments using an advanced MRI which can detect blood-brain barrier dysfunctionsPatients with cognitive impairmentsJPRN-UMIN000039724agoya City University100
Recruiting
Not Applicable
Psychiatric and cognitive function in patients with Neuroendocrine tumours with carcinoid syndrome.cognitieve stoornissencognitive impairmentdepression10027946NL-OMON45631ederlands Kanker Instituut85