CTRI/2020/10/028325尚未招募未知
Comparative study of Tocilizumab Vs Itolizumab in covid 19 Patient â??Randomized control trial
AIIMS Patna0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Age 18 to 60 years
- •2. Virological diagnosis of SARS-CoV2 infection
- •3. Patients who are in moderate ARDS following
- •COVID-19 infection, as defined by PaO2/FiO2
- •ratio of <200, or more than 25%
- •deterioration from the immediate previous
- •value within 24hrs in patient having
- •po2/fio2 >200.
- •4. Baseline serum ferritin level >=400ng/mL or
- •IL-6 levels greater than 4 times the upper
- •limit of normal (ULN) would be included.
排除标准
- •1. Known case of severe allergic reactions to
- •monoclonal antibodies
- •2. Active tuberculosis (TB) infection
- •3. History of inadequately treated tuberculosis
- •or latent tuberculosis
- •4. Have received oral anti-rejection or immune-
- •suppressive drugs within the past 6 months
- •5. Pregnant or breastfeeding, or positive
- •pregnancy test in a pre-dose examination
- •6. Patients with known history of Hepatitis
- •B, Hepatitis C or HIV
- •7. Absolute Neutrophils count (ANC) <1000 / mm3
- •8. Platelets <50,000 / mm3
- •9. Absolute Lymphocyte count (ALC): <500/mm3
- •10. Very severe ARDS Pao2/Fio2<=100 with PEEP>=5
- •11. ARDS due to others secondary infection/
- •bacterial sepsis (High procalcitonin value)
- •12. Those patient who will be recruited for
- •another study
研究者
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