Subjective Memory Complaints, Objective Memory Performance and Cognitive Training

Not Applicable

Completed

• Conditions: Anxiety Disorders; Fatigue Syndrome, Chronic; Chronic Pain; Depressive Disorder; Sleep Disorders
• Interventions: Behavioral: Control group; Behavioral: Cogmed working memory training

• Registration Number: NCT02156128
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The aim of this study is to examine if repetitive computerized cognitive training improves working memory in patients who are on sick leave due to complex symptom disorders (chronic pain, chronic fatigue, anxiety, depression and or sleep disorders), and whether effects of cognitive control training transfer to other tasks.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-10
• Study First Submitted: 2014-06-03
• Study First Submitted QC: 2014-06-04
• Study First Posted: 2014-06-05
• Primary Completion: 2015-03
• Study Completion: 2015-04
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-24
• Last Update Posted: 2017-01-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• on sick leave due to complex symptom disorders: chronic pain, chronic fatigue, anxiety, depression and/or sleep disorders
• on sick leave for at least eight weeks.

Exclusion Criteria

• severe mental disorder
• acute psychosis
• ongoing manic episode
• suicidal ideation
• ongoing abuse of alcohol or any other substance.
• not able to communicate in Norwegian

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group	Control group	These subjects will participate in the vocational rehabilitation program for 3,5 weeks. The program includes cognitive therapy (ACT) and physical activity, but no working memory training.
Cogmed	Cogmed working memory training	Participants in a 3,5 week vocational rehabilitation program (containing cognitive therapy and physical exercise) are instructed to use a computer-based working memory training program (named CogMed) each weekday (5 days a week) for 5 weeks. Each training session consists of 8 different tasks and lasts 40-50 minutes.

Primary Outcome Measures

Name	Time	Method
Working memory capacity	7 weeks	Objective memory performance as assessed by a sample of neuropsychological tests from Cambridge Cognition - Cantab tests (Spatial Working Memory (SWM), One Touch Stockings of Cambridge (OTS), Stop Signal Task (SST)) Including Paced Auditory Serial Addition Test (PASAT).

Secondary Outcome Measures

Name	Time	Method
Transfer to inhibition	7 weeks	Transfer to inhibition is demonstrated by significantly reduced Stop Signal Reaction Time on The Stop Signal Task
Subjective memory complaints (SMC)	7 weeks	Subjective memory complaints (SMC) are measured by a self-report questionnaire "The Everyday Memory Questionnaire" We estimate prevalence of subjective memory complaints and examine the correspondence between SMC and symptoms of depression, anxiety, sleep disturbances, chronic fatigue and chronic pain.

Trial Locations

Locations (1)

NKSS Nasjonal kompetansetjeneste for sammensatte symptomlidelser; 🇳🇴 Trondheim, Norway