CTRI/2025/07/091228尚未招募不适用
A randomized comparative clinical trial to evaluate the efficacy of Bharangimool churnavati and Nirgundi ghanavati in the management of Gridhrasi.
PDEAs College of Ayurveda and Research centre Nigdi pradhikaran Pune1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2025年8月2日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- 1.To compare the efficacy Of Bharangimool churnavati and Nirgundi Ghanvati In relieving pain given for 21 days in management of Gridhrasi
研究概览
简要总结
- In the present era, lifestyle trends are shifting away from healthy living, leading to an increase in various health issue, One such condition is Gridhrasi, is a nanatmaj vata vyadhi Lower back pain is an incredibly common musculoskeletal disorder that affects leg movement. Among patients experiencing this condition, approximately 40% suffer from radicular pain, which can be classified as part of the sciatica syndrome. Gridhrasi , which manifest as pain starting from the lower back (kati) and radiating down to the buttocks, thighs (uru) Knees ( Janu), Calves and feet.
- This pain pattern closely resembles sciatica, a debilitating condition where hip pain extends downs the leg and foot due to compression of sciatic nerve.
- In modern medicine Gridhrasi correlated with sciatica
- In modern medicine sciatica pain is managed by using anti- inflammatory, muscle relaxants, physiotherapy and even the surgical intervention but the chances of re-occurrence as well.
- Ayurveda provides several effective options in the management of Gridhrasi.
- Vataj Gridhrasi – This type is characterized by stiffne ( Stambha), Pricking pain (toda), twitching or trembling sensation( Spandana) and severe pain (Ruk) Orginating from the gluteal region (sphik pradesha) the pain radiates down to various body parts, including the pelvis ( kati), back ( Prushta) thigh( Uru) Knee (janu), foot (paada)
- Vata- Kaphaj Gridhrasi – in addition to the symptoms mentioned above this type presents with lethargy (tandra), Heaviness ( Gaurav) and loss of appetite ( Aruchi)
Study Rationale:
- Although lots of work have been done in the management of Gridhrasi , still alternative medicines are required
- Bharangimool churnavati is easily available and cost effective, In modern medicine painkillers give symptomatic relief only.
- No other work has been done on the effect Bharangimool churnavati in the management of Gridhrasi, hence this formulation has been selected for the study .
- In the treatment of Gridhrasi drug of choice should have Vatashamak, kaphashamak Bharangi have both vatshamak and kaphashamak properties.
- Bharangimool churnavati is mentioned in Gadanigrah having all properties may reverse the pathogenesis of Gridhrasi.
- A rational of the study To compare the efficacy Of Bharangimool churnavati with Nirgundi Ghanvati for relieving the symptoms of Gridhrasi.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 25.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •1.SLR test positive patient with the help of goniometer. 2.Patients in the age group of 25-60 years ,irrespective of religion,caste,gender and socioeconomic status. 3.Patient with classical signs of Gridhrasi jaanujanghapadam kramat and sakthikshepnigrahanat should be there 4.Radiating pain from kati pradesh (lower back) to paad ( foot )should be there . Radiating pain along the course and distribution of sciatic nerve 5.Associated symptoms are- Patients having two or more following symptoms.
- •katishool (lower back pain) spand (throbbing /pulsating) toda (pricking sensation ) aruchi ( anorexia) Gourav(heaviness) paadshool (leg pain ).
排除标准
- •1.Patients having congenital anomalies with lumbosacral spine kyphosis, scoliosis, lordosis.
- •2.Known case of Spondylolisthesis, sacroiliac arthritis.
- •3.Known case of uncontrolled diabetes mellitus , deep vein thrombosis.
- •4.Pregnant and lactating mothers.
- •5.Patients with paraplegia of lower limb.
- •7.Known case of Infective disorders –tuberculosis of Spine, osteomyelitis of spinal bone.
- •8.Patients with deep wounds penetrating till sciatic nerve.
- •10.Patients having allergy to any content of drugs.
结局指标
主要结局
1.To compare the efficacy Of Bharangimool churnavati and Nirgundi Ghanvati In relieving pain given for 21 days in management of Gridhrasi
时间窗: 21 Days with follow up on 8th,15th,22nd day
次要结局
- 1.To compare the efficacy Of Bharangimool churnavati and Nirgundi Ghanvati for relieving other symptoms given for 21 days in management of Gridhrasi .(2.To observe and compare the adverse effects in two groups within 21 days)
研究者
Dr Rutuja Chandrakant Solunke
PDEAs college of ayurved and Research centre Nigdi pune 411044
研究点 (1)
Loading locations...
相似试验
尚未招募
不适用
To study the effect of kushmanda swarasa and kapittha swarasa in gastritisCTRI/2025/02/080595Dr Tejaswini R50
尚未招募
2/3 期
Effect of Shigru Taila Nasya and Anu Taila Nasya in management of Vataja Pratishaya (Allergic Rhinitis)CTRI/2024/12/078578Smt K C Ajmera Ayurved Mahavidyalya DeopurDhule70
Enrolling By Invitation
不适用
Adolescent Lifestyle Medicine Headache StudyNCT07373275MaineHealth50
尚未招募
不适用
Compare Effect Of Navayasa Churna And Dadima Swaras Along With Navayasa Churna In Management Of Panduroga(Anemia).CTRI/2025/10/095793Smt K C Ajmera Ayurved Mahavidyalya Deopur Dhule50
尚未招募
2 期
A clinical study to assess the role chandrashoor seeds (ahaleev) to increase bala i.e strength of individuals with generalised weakness.CTRI/2025/02/081355PDEAs College of Ayurved and Research center, Nigdi Pune-41104440
