Effects of Handwriting Exercise on Functional Outcome in Parkinson’s Disease: A Randomized Controlled Trial

Not Applicable

Completed

• Conditions: Parkinson' s disease; Handwriting; micrographia; fine motor function; handwriting exercise

• Registration Number: TCTR20190627004
• Lead Sponsor: Faculty of Medicine Ramathibodi Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-12-31
• Study Start: 2019-06-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

The diagnosis of Parkinson’s disease was made according to United Kingdom Parkinson’s Disease Society Brain Bank criteria, however family history of PD was allowed. Inclusion criteria included that patients must be at least 18 years of age, Hoehn and Yahr (H&Y) stage 1-3 during an on-medication period, on stable pharmacological treatment without motor fluctuations at least for the past 6 weeks, and able to write.

Exclusion Criteria

Patients with coexisting neurological or musculoskeletal disorders affecting writing movement and patients who underwent deep brain stimulation were excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
an improvement in the time taken to complete the 1-page handwriting test 4 weeks the time taken to complete the 1-page handwriting test at baseline and at 4 weeks after intervention

Secondary Outcome Measures

Name	Time	Method
time used to complete the test, accuracy of writing, patient’s subjective rating 4 weeks change from baseline in these parameters