Effectiveness of probiotics yoghurt on treatment and recurrence of bacterial vaginosis
- Conditions
- Bacterial Vaginosis.other inflammation of vagina and vulva
- Registration Number
- IRCT201206243706N13
- Lead Sponsor
- Infectious disease research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 140
1- Married, non pregnant, non lactatating women aged 49-15 years
2-diagnosis of bacterial vaginosis by Amsel and Nugent Criteria).
3 - no abnormal vaginal bleeding.
4 - no probable intervening situations with the test results (menstruation at time of smear, having sex during last 48 houres, use of douch during last 48 houres)
5 -giving informeed consent to participate the study and be able to present at the clinic during next 24 houres, once every 2 weeks for next 2 month (to get the yoghurts), and also after 3 months, and after 6 months for assessments.
Exclusion criteria:
1 - use of antibiotics in last 2 weeks.
2 - use of vaginal drugs in last 30 days.
3 - suffering from HIV.
4 - suffering from heart disease and kidney failure.
5 - Having surgery on the colon.
6 – smoking.
7 - Starting to use IUD in the last month or deciding to Insert IUD in following 3 months.
8 - useing immunosuppressive drugs.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Microbiological cure. Timepoint: 10+-2 days after starting treatment. Method of measurement: Microbiologocal cure as assessed by Amsel criteria and Nugent score.;Recurrence of bacterial vaginosis. Timepoint: 90 and 180 +- 7 days after starting treatment. Method of measurement: Amsel criteria and Nugent score.
- Secondary Outcome Measures
Name Time Method Clinical cure. Timepoint: 10 +- 3 days and 90 and 180 +-7 days after starting treatment. Method of measurement: Patient and clinician reports.