Risk taking during decision-making under stress: The effects of psychological stress on risk taking in feedback-based decision making

Completed

Conditions: Geen aandoening als zodanig, gezonde participanten worden onderzocht.
Not applicable

Registration Number: NL-OMON40090

Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 60

Inclusion Criteria

Age 18-65, male or female
Normal or corrected-to-normal vision

Exclusion Criteria

- Drug or alcohol abuse over a period of six months prior to the experiment
- Unwillingness to view or hear aversive stimuli from the IAPS or IADS
- Previously diagnosed with, or under treatment for, psychological or psychiatric disorders (e.g. depression, schizophrenia, neuroticism, etc.).
- Previously diagnosed with, or under treatment for, medical indications (e.g. closed- or open-head injury, neurological illness, epilepsy, PTSD, cardiovascular indications, endocrinological dysfunction, etc.).
- Use of medication (chronic/recently)
- Pregnancy
- Ferrous objects in or around the body (e.g. braces, glasses, pacemaker, metal fragments)
- Claustrophobia

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Study 1<br /><br>The measured physiological stress responses (heart rate, systolic and diastolic<br /><br>blood pressure and electrodermal response) and cortisol response during all<br /><br>tasks.<br /><br><br /><br>Study 2<br /><br>The amplitude of the P300 and Feedback Related Negativity (FRN) component in<br /><br>response to both positive and negative feedback in the BART task during<br /><br>different stressor intensities.<br /><br><br /><br>Study 3<br /><br>The BOLD response in the striatum, anterior cingulate cortex, insula,<br /><br>dorsolateral and ventromedial prefrontal cortex, amygdala, and orbitofrontal<br /><br>cortex in response to positive and negative feedback and during<br /><br>decision-making, during different stressor intensities, during all BART trials.</p><br>

Secondary Outcome Measures