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Head Position in Stroke Trial

Not Applicable
Conditions
Acute Ischaemic and Haemorrhagic Stroke
Registration Number
SLCTR/2015/025
Lead Sponsor
Professor Craig Anderson
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow up complete
Sex
Not specified
Target Recruitment
700
Inclusion Criteria

1. Adults aged >18 years (the age for adults may vary in different countries)
2. Presumed clinical diagnosis of acute stroke (i.e. with a persistent neurological deficit on presentation)
3. Present to hospital, or have an in-hospital event or transfer from another hospital, with an acute stroke.

Exclusion Criteria

1. Transient ischemic attack (TIA) (i.e. symptoms fully resolved upon presentation)
2. Definite clinical contraindication or indication to either sitting up or lying flat head positions
3. Significant medical condition that takes priority in care and where adherence to the randomized head position is not possible on another ward/department of the hospital
4. Immediate transfer from the Emergency Department (ED) or admission, to another ward for medical treatment (e.g. for haemodialysis) or surgery (e.g. carotid endarterectomy, haematoma evacuation) where adherence to the randomized head position is not possible.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
A shift (‘improvement’) in death or disability according to the patient’s modified Rankin Scale (mRS) at 90 days. [90 days ]<br>
Secondary Outcome Measures
NameTimeMethod
1. A shift in NIHSS score<br>2. Death<br>3. Length of hospital stay<br>4. The European Quality of Life Scale 5 Dimension (EQ-5D)<br>5. Pneumonia<br> [1. 7 days<br>2. 90 days<br>3. At discharge<br>4. At 90 days<br>5. Occurrence 48 hours or more after admission, which was not incubating at the time of admission<br>]<br>
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