NL-OMON46010已完成不适用
Whole-Exome Sequencing in Dutch Children with PSC - WHELP-study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 2 至 99（—）
入选标准
- •This study involves two groups of participants:
- •(1) An affected individual who developed PSC before the age of 13, and in whom PSC was confirmed with either cholangiography or liver biopsy
- •(2) Parents of participants of group 1 ;Eligible candidates of group 1 can have any age.
- •Confirmation of PSC by imaging is defined as the presence of multifocal strictures, focal dilatation, or beading of the biliary tree. Histological confirmation is defined as the presence of bile duct damage, onion-skinned peri-ductal fibrosis, inflammation, portal edema or fibrosis, ductopenia, ductular proliferation, or cholestasis
排除标准
- •Patients with PSC due to secondary causes such as surgery, trauma, cancer or infection will be excluded from participation in this study
研究者
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