Proof of concept study of TY-51924 in patients with acute myocardial infarctio

Phase 2

• Conditions: Acute myocardial infarction

• Registration Number: JPRN-jRCT2080221705
• Lead Sponsor: TOA EIYO LTD.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-30
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1) Admission to hospital within 6 hrs of the onset of symptoms
2) Chest pain lasting for >= 30 min
3) ST-segment elevation of >= 0.2 mV in 2 or more contiguous precordial leads (V1-V4) on standard 12-lead electrocardiogram
4) TIMI flow grade 0/1 in left anterior descending artery (LAD) on diagnostic coronary angiography (CAG)
5) Written informed consent

Exclusion Criteria

1) Prior documented old myocardial infarction (MI) or a clinical history of definite MI
2) Left main trunk (LMT) stenosis >50%
3) Total occlusion of left circumflex artery (LCX) or right coronary artery (RCA)
4) Left bundle-branch block
5) Suspected acute aortic dissection
6) Cardiac arrest or cardiogenic shock
7) Thrombolytic therapy or coronary artery bypass grafting (CABG)
8) Hepatic and/or renal dysfunction
9) History of allergy or drug hypersensitivity
10) Pregnancy or nursing mothers or childbearing women

Study & Design

• Study Type: Interventional
• Study Design: Not specified