Evaluation of the effect of venous anesthesia during Gallbladder Removal Surgery on pain intensity and acute inflammatory response

Phase 4

• Conditions: C23.550.767; Cholecystectomy Laparoscopy; Postoperative Pain

• Registration Number: RBR-48wwhsw
• Lead Sponsor: Hospital São Domingos

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-12-01
• Study Start: 2023-10-10
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients over 18 years of age, ASA I-III, of both genders, who underwent videolaparoscopic cholecystectomies were included in the study.

Exclusion Criteria

Patients who had cardiac arrhythmias, dilated cardiomyopathy, cardiac conduction disorders, electrolyte disorders, acid-base disorders, hypersensitivity to lidocaine, psychiatric, liver, respiratory or oncological diseases, who had been receiving any type of analgesic in the previous week were excluded from the study, surgery and those who received blood products during the study period.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected outcome I: It is expected to find a decrease in pain intensity from 30 minutes to 12 hours postoperatively, verified using the pain analogue scale, based on the verification of a variation of at least 2 points in the comparative measurements between the two groups.;Expected outcome II:It is expected to find a decrease in the consumption of analgesia by patients in the postoperative period, verified through the analysis of 3 variables: first dose of morphine administered (in minutes), dose of morphine administered (in mg) and use of morphine, the from the verification of a p value <0.05 in the statistical comparison between the groups.