Avoidant and Restrictive Food Intake Disorders (ARFID) in Adolescence: Early Oral Development, Psychopathological Profile and Sensory Integration

Not yet recruiting

• Conditions: Avoidant and Restrictive Food Intake Disorders

• Registration Number: NCT06665802
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

The purpose of this study is to assess if adolescents affected with Avoidant and Restrictive Food Intake Disorders (ARFID) had more frequent precocious pediatric feeding disorders before 4 years old compared to healthy adolescents.

Detailed Description

This research focuses on retrospective analysis of early pediatric feeding disorders seen for ARFID in adolescence in two departments of the DMU MEFADO.

This assessment will be implemented during a hospital visit by a questionnaire completed by the patient's parents covering the first years of the child's life in medical, behavioural and dietary terms. This questionnaire was created for this study and, therefore, is not validated for general population. The parents will also complete the Montreal Children Feeding scale based on their memories.

The Montreal Children Feeding scale is a validated parental self-questionnaire, allowing the screening of feeding and eating disorders in children under 6 years old. Since the study specific questionnaire is not validated, 60 non-ARFID controls will be included in the study for questionnaires completion. The research also focuses on the psychopathological profile of these adolescents with ARFID regarding their degree of anxiety, their degree of depression, their possible autistic traits and their sensory sensitivity. These aspects will be studied by validated self- and hetero-questionnaires standardized for these fields. The emotional expression of the parents will be assessed during a brief qualitative interview type "Five-Minute Speech Sample".

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Status Verified: 2024-10
• Study First Submitted: 2024-10-24
• Study First Submitted QC: 2024-10-28
• Last Update Submitted: 2024-10-28
• Study First Posted: 2024-10-30
• Last Update Posted: 2024-10-30
• Study Start: 2024-11
• Primary Completion: 2024-11
• Study Completion: 2025-11

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

For all patients:

• Adolescent aged 12 to 18 (minors = 17 years 11 months)
• No opposition from parents and adolescent

For ARFID patients:

• Consulting at MDA or Necker for an ARFID diagnosed using DSM V criteria
• Whose first consultation for this disorder was less than 2 years ago

For non-ARFID patients:

• Consulting or hospitalized in orthopaedic surgery at Necker Hospital or Robert Debré Hospital for an acute traumatic reason
• Not diagnosed with a chronic illness

Read More

Exclusion Criteria

For all patients:

• Parents and adolescents who do not speak French well enough to understand the questions on the scales and questionnaires

For ARFID patients:

• Diagnosis of autism spectrum disorder already made at the time of the consultation

For non-ARFID patients:

• Presence of a chronic organic or psychological illness, to limit the risk of including non ARFID patients at high risk of eating disorders

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of pediatric feeding disorders (PFD)	1 day	Determine whether adolescents recently diagnosed with ARFID have more frequent FPD before the age of 4 years compared to adolescents without ARFID by using the Montreal scale score (61 or more) and/or the specific study questionnaire (at least 4 positive answers)

Secondary Outcome Measures

Name	Time	Method
Depression in ARFID adolescents	1 day	Determine whether adolescents recently diagnosed with ARFID have more frequent depression compared to adolescents without ARFID by using the ADRS (Adolescent Depression Rating Sclale) (score of 4 or more)
Severity of eating disorders on growth consequences in ARFID adolescents	1 day	Evaluation of growth effects of ARFID by measuring the Z score and Tanner stage.
Sensory profile in ARFID adolescents	1 day	Determine whether adolescents recently diagnosed with ARFID have more frequent hypersensoring or hyposensoring traits compared to adolescents without ARFID by using Sensoring Processing Scale Inventory (SPSI)
Autistic traits in ARFID adolescents	1 day	Determine whether adolescents recently diagnosed with ARFID have more frequent autistic traits compared to adolescents without ARFID by using the Autism Spectrum Screening Questionnaire (ASSQ) (score of 13 or more)
Parental profile in ARFID adolescents	1 day	Compare parent's emotional expression for adolescents recently diagnosed with ARFID to adolescents without ARFID by using the five minute speech sample.
Anxiety in ARFID adolescents	1 day	Determine whether adolescents recently diagnosed with ARFID have more frequent anxiety compared to adolescents without ARFID by using the GAD-7 scale (score of 5 or more)

Trial Locations

Locations (3)

Hôpital Cochin; 🇫🇷 Paris, France

Hôpital Necker - Enfants malades; 🇫🇷 Paris, France

Hôpital Robert Debré; 🇫🇷 Paris, France