A sham-treatment-controlled, randomized single-blinded study on the influence of 6 weeks of prehabilitation training under local muscular hypoxia (Blood Flow Restriction Training) prior to arthroscopic anterior cruciate ligament replacement on knee joint function, morphology and strength. - BFR-Prehab

BG Klinikum Duisburg gGmbH0 个研究点目标入组 40 人开始时间: 2024年3月19日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•BMI: male 20-30, female 19-30
•- Tegner score 4-9
•Irritation-free knee joint:
•- Pain: VAS [1-10]: < 3
•- Swelling: circumference [cm] < 3 (5cm < center of patella > 5cm)
•- Heat: temperature [°] < 2
•- Function: 10 squats without additional load
•- Unilateral ACL rupture including concomitant injuries requiring treatment (e.g. partial meniscus resection), from which no changed follow-up treatment is derived

•Cardiovascular diseases:
•- Coronary heart disease
•- Existing or increased risk of venous thromboembolism
•- Increased risk of hemorrhagic stroke
•- Increased risk of exercise-induced rhabdomyolysis
•- Increased risk of atrial fibrillation or heart failure
•- Previous use of medications known to increase the risk of blood clotting
•- Induration/Marfan syndrome
•- Vascular endothelial dysfunction
•- Previous hemophilia
•- Cardiopulmonary diseases
•- Silent myocardial ischemia
•- Left ventricular dysfunction
•- Iatrogenic changes in the arterial/venous vessels of the lower extremities
•- Inserted stents, bypasses
•- sickle cell anemia
•Other exclusion criteria:
•- Pregnancy
•- Oncological history
•- Acute or chronic infections
•- Inability to undergo surgery
•- Open wounds or infections of the extremities to be trained
•- Acute compartment syndrome
•- Acute need for surgery (e.g. incarceration of the meniscus) and significant changes to the post-treatment protocol (e.g. suturing of the meniscus)

发起方