Effects of Non-Steroidal anti- inflammatory drugs on pulp sensibility test on diabetic patients with symptomatic irreversible pulpitis - A Double Blinded Randomized Clinical Trial

Diabetes mellitus is a chronic inherited or acquired disorder caused by low production or ineffectiveness of insulin produced by the pancreas glands. Diabetes is a metabolic disease that is induced because of hyperglycemia. Hyperglycemia may result from either impairment of secretion or malfunction of insulin or both. There are several types of diabetes, but type 2 diabetes is the most frequent form.

 Diabetes mellitus not only induces dental pulp metabolic changes, but also it has been shown that it can influence both sensory and vascular structures. Therefore, it can be hypothesized that diabetes might affect pulp responses to sensibility tests. Pulpal sensibility tests, such as the cold, heat, and electric pulp tests (EPT) are important tools in endodontic diagnosis. The cold test is one of the most common endodontic diagnostic tests for the indirect assessment of the pulp vitality. It is usually performed in combination with EPT to increase the validity and reliability of the findings. Thisclinical trial aims to interpret and analyze the pulp sensibility in controlled Type II Diabetics and Healthy patients with symptomatic irreversible pulpitis.