Improvement of Language Disturbances After Stroke by Intensive Training and Electrical Brain Stimulation

Phase 2

• Conditions: Aphasia; Stroke
• Interventions: Device: anodal tDCS; Device: cathodal tDCS; Device: sham stimulation

• Registration Number: NCT00822068
• Lead Sponsor: University Hospital Muenster

Brief Summary

The study aims to identify if intensive language training, consisting mainly of computer-based object naming, together with electrical brain stimulation, will lead to an improvement of language functions in patients that suffer from language disturbances after a stroke.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-01
• Study Start: 2009-01
• Study First Submitted: 2009-01-13
• Study First Submitted QC: 2009-01-13
• Last Update Submitted: 2009-01-13
• Study First Posted: 2009-01-14
• Last Update Posted: 2009-01-14
• Primary Completion: 2009-12
• Study Completion: 2009-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• chronic stroke (> 1 year after event)
• aphasia due to stroke with naming impairment
• German as first language
• first-ever stroke

Exclusion Criteria

• more than 1 stroke
• progressive stroke
• history of severe alcohol or drug abuse, psychiatric illnessess like severe depression, poor motivational capacity
• dementia
• contraindications for Magnetic Resonance Imaging

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
anodal tDCS	anodal tDCS	-
2	cathodal tDCS	cathodal tDCS
3	sham stimulation	sham stimulation

Primary Outcome Measures

Name	Time	Method
Number of words correctly named after training plus tDCS	1 year

Secondary Outcome Measures

Name	Time	Method
Communicative-Activity-Log & Stroke-and-Aphasia-Quality-of-Life-Scale	1 year

Trial Locations

Locations (1)

Department of Neurology, University of Muenster; Department of Neurology, University of Berlin; 🇩🇪 Muenster / Berlin, NRW/Berlin-Brandenburg, Germany