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临床试验/NL-OMON48431
NL-OMON48431已完成不适用

se of Copeptin Measurement after Arginine Infusion for the Diagnosis of Diabetes Insipidus - the CARGOx Study - CARGOx

Prof. Mirjam Christ-Crain, University Hospital Basel (USB)0 个研究点目标入组 30 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • 1. Age >= 18 years
  • 2. Hypotonic polyuria / polydipsia syndrome defined as:
  • polyuria >50ml/kg body weight/24h and polydipsia >3l /24h or known diabetes
  • insipidus under treatment with DDAVP
  • Urine-Osmolality <800mOsm/L

排除标准

  • 1. Polyuria / polydipsia secondary to diabetes mellitus, hypercalcemia or
  • hypokalemia
  • 2. Nephrogenic diabetes insipidus (defined as baseline copeptin level
  • >21.4pmol/L)
  • 3. Evidence of any acute illness
  • 4. Epilepsy requiring treatment
  • 5. Uncontrolled arterial hypertension (blood pressure >160/100mmHg at baseline)
  • 6. Cardiac failure (NYHA III-IV)
  • 7. Liver cirrhosis (Child B-C)
  • 8. Uncorrected adrenal or thyroidal deficiency
  • 9. Patients refusing or unable to give written informed consent
  • 10. Pregnancy or breast feeding
  • 11. End of life care

研究者

发起方
Prof. Mirjam Christ-Crain, University Hospital Basel (USB)

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