A multicenter randomized double-blind controlled study on the staged prevention and treatment of early retinal degeneration in high myopia by combining disease and syndrome
- Conditions
- Retinal degeneration of high myopia
- Registration Number
- ITMCTR2200006531
- Lead Sponsor
- Eye Hospital of China Academy of Chinese Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1. Diopter = -6.00D and axial length = 26mm
2. Age :20-60
3.HM patient had stage A1 macular lesions and qi and blood deficiency syndrome: if the patient met 1 main symptom +1 secondary symptom, he could be included in the group
4.HM patient had stage A2 macular lesions and qi deficiency and blood stasis syndrome: if the patient met 1 main symptom +1 secondary symptom, he could be included in the group
5. Other vasodilators or neurotrophic drugs are being used and can be included after 1 month of drug withdrawal
6. Informed consent has been signed
1. Have HM macular cleft, retinal hiatus, neovascularization, retinal detachment, glaucoma and other fundus lesions
2. Accompanied by cardiac, hepatic and renal insufficiency
3. Patients who are participating in clinical trials of other drugs or who are using the same traditional Chinese medicine and other treatments together
4. Patients suffering from hypertension, diabetes and other systemic diseases
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total retinal blood flow density in macular area;
- Secondary Outcome Measures
Name Time Method Spherical Equivalent Refraction;Mean retinal thickness in macular area;The thickness of the mGCC;TCM syndrome score;best corrected visual acuity;axial length;Choroid thickness under macular fovea;