Tubular and glomerular damage markers in urine and blood samples in diabetic patients.
Recruiting
- Conditions
- diabetic nephropathy1001265310029149
- Registration Number
- NL-OMON32838
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
age > 18 years
diabetes mellitus
albuminuria (40 patients with normo-albuminuria, 40 with micro-albuminuria and 20 with macro-albuminuria will be included)
Exclusion Criteria
lacking retinopathy when having albuminuria (micro or macro)
primary renal disease other than diabetic nephropathy
mentally incapacitated
erythrocyturia (more than 25 per field of vision)
Use of nephrotoxic medication
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Study parameters are the concentration tubular and glomerular biomarkers and<br /><br>urine albumin excretion. </p><br>
- Secondary Outcome Measures
Name Time Method <p>association with renal function (measured as eGFR)<br /><br>association with diabetes control (measured as HbA1c)</p><br>