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Clinical Trials/NCT00437931
NCT00437931CompletedNot Applicable

Color Flow Doppler Ultrasound in Subclinical Thyroid Dysfunction

HaEmek Medical Center, Israel1 site in 1 country60 target enrollmentStarted: February 2007Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
60
Locations
1

Study Overview

Brief Summary

Overt hyperthyroidism and hypothyroidism are associated with inverted hemodynamic changes.Regional blood flow disturbances (including intrathyroidal) were also reported in these thyroid disorders. The purpose of this study is to investigate the thyroid vascularity and blood flow by Color Flow Doppler Sonography in patients with subclinical thyroid dysfunction

Detailed Description

Color Flow Doppler Sonography (CFDS) has become in the last years an increasing procedure to assess the thyroid blood flow. Previous studies showed specific changes of thyroid blood flow in hyperthyroidism, Hashimoto's thyroiditis and thyroid nodules when investigated by CFDS. Subclinical hyperthyroidism and hypothyroidism are common laboratory findings, defined by normal thyroid hormones concentrations along with ,respectively,decreased or increase Thyroid stimulating hormone (TSH) level. We purpose to investigate thyroid vascularity by CFDS in patients with subclinical hyperthyroidism or hypothyroidism and compared them with euthyroid patients.

Study Design

Study Type
Observational
Observational Model
Case Control
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to 75 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • patients with subclinical hypothyroidism or hyperthyroidism
  • patients with thyroid nodules and normal thyroid function

Exclusion Criteria

  • patients who are taking thyroxine, antithyroid drugs, lithium or amiodarone
  • patients who had thyroid surgery or radioiodine therapy
  • patients with NYHA class 3 or 4 heart failure

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

avraham ishay

Dr

HaEmek Medical Center, Israel

Study Sites (1)

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