Centchroman vs tamoxifen in patients with breast pai
- Conditions
- Health Condition 1: N644- Mastodynia
- Registration Number
- CTRI/2023/11/059992
- Lead Sponsor
- on-funded
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1. All female patients, aged >18 years
2. Patients, who have complain of mastalgia with or without breast fibroadenoma having persistent symptoms for more than 1 month after reassurance and supportive breast management.
3. Pain severity of >3/10 on visual analog scale.
1. Acute inflammatory breast conditions (cellulitis , breast abscess)
2. suspicion of malignancy ( clinical or radiological)
3. Family history of breast and ovarian carcinoma
4. Contraindication to centchroman and tamoxifen —--
a.Pregnancy
b.Polycystic ovarian diseases ( PCOD )
c.Cervical hyperplasia do
d.Recent history or clinical evidence of jaundice or liver diseases
e Conditions like, chronic illness such as tuberculosis, renal diseases, severe allergic states etc.
f.Patients willing to conceive within six months.
5.History of chest trauma
6.Severe drug reaction to either centchroman or tamoxifen after starting treatment
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The comparison of pain score in the mastalgia patients with or without fibroadenoma undergoing treatment with centchroman and tamoxifen with Visual analog scale at end of 3 month treatment. <br/ ><br>Timepoint: Visual analog scale at end of 3 month treatment. <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method To compare the response in size of fibroadenoma <br/ ><br>To compare patient satisfaction with likert scale <br/ ><br>Timepoint: Visual analog scale at end of 3 month treatment. <br/ ><br>