Comparison of analgesic effects of intravenous infusion of Lidocaine and Ketamine on acute pain after elective laparotomy surgery in patients of two groups of purpose and control

Phase 3

• Conditions: Acute pain after elective laparotomy surgery.; Other acute post-procedural pain; G89.18

• Registration Number: IRCT2017071935187N1
• Lead Sponsor: Vice chancellor for research, Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

ASA I, ASA II, Hb>10, elective laparotomy surgery, consent to participation, no important underlying disease.
Exclusion criteria: uncontrolled underlying disease, addiction to alcohol and opioids, sensitivity to opioids, Ketamine or Lidocaine, weight>115kg, height<140cm.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of acute pain after elective laparotomy surgery. Timepoint: Just after surgery, 6 hrs after surgery, 12 hrs after surgery, 18 hrs after surgery, 24 hrs after surgery. Method of measurement: Visual analog scale.

Secondary Outcome Measures

Name	Time	Method
Seizure. Timepoint: Any time after beginning of signs & symptoms. Method of measurement: Patient and support person's complaint.;Cardiac arrhythmia. Timepoint: Any time after beginning of signs & symptoms. Method of measurement: Patient and support person's complaint and ECG.;Halucination. Timepoint: Any time after beginning of signs & symptoms. Method of measurement: Patient and support person's complaint.;Nausea & Vomiting. Timepoint: Any time after beginning of signs & symptoms. Method of measurement: Patient and support person's complaint.;Delirium. Timepoint: Any time after beggining of signs and symptoms. Method of measurement: Patient and support person's complaint.;Drug sensitivity. Timepoint: Any time after beginning of signs & symptoms. Method of measurement: Patient and support person's complaint.