Research on the Development and Validation of an Early Prediction Model for Delirium Based on Machine Vision Analysis
概览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 795
- 主要终点
- Number of participants with delirium as assessed by DSM-5
概览
简要总结
Delirium has a high incidence rate and significantly affects patient prognosis. Diagnosis often relies on manual assessment, which is subject to strong subjectivity, high rates of missed diagnosis, and poor stability. This study employs non-contact identification technology based on machine vision analysis to quantitatively analyze characteristic biological feature data such as micro-expressions. It then investigates the correlation between these features and delirium subtypes. By integrating clinical phenotypic data and using machine learning algorithms, a multi-modal early prediction model for delirium is constructed to meet the clinical need for early warning of delirium subtypes and enhance the efficacy of delirium identification.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years, expected ICU stay ≥ 24 hours, and informed consent to participate in this study;
排除标准
- •Patients with severe facial trauma/deformities that prevent complete expression acquisition, and patients with a history of emotional problems (such as anxiety, depression, etc.).
研究组 & 干预措施
observational
- Meets the delirium diagnostic criteria specified in the Diagnostic and Statistical Manual of Mental Disorders (5th Edition) (DSM-5), which requires the concurrent presence of: ① disturbance in awareness (reduced clarity of awareness of the environment) ; ② change in cognition (e.g., memory impairment, disorientation);
- Undergoes consecutive daily assessments for 7 days using the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) at three time points (8:00, 14:00, 20:00) with an interval of ≥ 6 hours between each assessment, with at least two positive results;
control
Admitted to the ICU during the same period, with negative results on consecutive daily CAM-ICU assessments for 3 days (three assessments per day as the observational group).
结局指标
主要结局
Number of participants with delirium as assessed by DSM-5
时间窗: 7th day after ICU admission
Zero is equivalent to no delirium and a high score means a higher occurrence of delirium
次要结局
- Accuracy(7th day after ICU admission)
- Precision(7th day after ICU admission)
- Recall(7th day after ICU admission)
- F1-score(7th day after ICU admission)