跳至主要内容
临床试验/CTRI/2025/01/079602
CTRI/2025/01/079602招募中不适用

Fracture Evaluation Management & Understanding Research (FEMUR): A prospective global cohort study

University of Birmingham17 个研究点 分布在 1 个国家目标入组 4,424 人开始时间: 2025年2月7日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
4,424
试验地点
17
主要终点
- To audit mortality, morbidity, and mobility outcomes 30 days after admission with

研究概览

简要总结

The femur is the largest bone in the body and femur fractures are common after injuries, globally. Femur fractures are psychologically traumatic for patients, causing severe pain and disability or death if not well managed. Multiple types of femur fracture exist, with some types being associated with high mortality rates and disability than others. However, evidence also suggest that for any given type of femur fracture, outcomes vary dramatically dependent on the geographical location of the patient. Patient age, sex, delays prior to receiving management, duration of surgery, preoperative physiological state, and management received also influence outcomes.

Evidence on outcomes after femur fracture and comparisons between management strategy and geographical regions is useful for raising awareness of disparities in quality of care and for health system planning. This evidence is currently lacking from the global literature.

The aim of this study is to understand the management provided for different types of femur fractures that are admitted to hospitals globally, and the outcomes for patients with these fractures.

  1. To audit mortality, morbidity, and mobility outcomes 30 days after admission with femur fractures globally

  2. To describe the management of femur fractures in hospitals globally

In comparing outcomes by management received, facility type, and global location, we will provide data to inform health system planning and utility for global advocacy.

This is a prospective, multicentre, cohort study conducted by the FEMUR Collaborative. The Collaborative consists of an international central team, national leads, hospital leads, and data collection teams. National and hospital leads will be purposely recruited through personal invitations to colleagues, orthopedic professional associations and informal networks, the rural doctor’s association, and social media. The central team will provide support to national and hospital leads through monthly webinars and WhatsApp group chats.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • Adult (over 18 years of age) participants of any sex who are admitted to a facility for definitive management of a femur fracture.
  • Patients receiving emergency and elective procedures should be included.
  • Patient management can include non-operative and/or operative treatment of the femur fracture.

排除标准

  • Minors under 18 years of age will be excluded.
  • Repeat hospital admissions for the same femur fracture will be excluded.

结局指标

主要结局

- To audit mortality, morbidity, and mobility outcomes 30 days after admission with

时间窗: 30 day follow up

femur fractures globally

时间窗: 30 day follow up

- To describe the management of femur fractures in hospitals globally

时间窗: 30 day follow up

次要结局

未报告次要终点

研究者

申办方类型
Research institution
责任方
Principal Investigator
主要研究者

Dr Bobby John

Christian Medical College & Hospital Ludhiana

研究点 (17)

Loading locations...

相似试验