Comparison of the effect of Adalimumab and Methotrexate in the treatment of psoriasis

Phase 2

Recruiting

• Conditions: L40.1; Moderate to sever of psoriasis.; Generalized pustular psoriasis

• Registration Number: IRCT20100102002954N26
• Lead Sponsor: Shahroud University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 8 March 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

Age range 55-15 years;
Patients with a definite diagnosis of moderate to severe psoriasis;
Having the satisfaction of participating in the project.

Exclusion Criteria

History of severe burns or skin damage;
Existence of severe chronic hormonal disorders such as hypothyroidism;
History of severe hirsutism;
History of topical treatment of psoriasis with drugs and combined solutions in the last six months;
History of skin laser in the past year;
History of chronic liver and kidney disease;
History of hormone therapy (estrogen or testosterone),
Pregnancy or lactation,

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Measurement of psoriasis severity index. Timepoint: Beginning and end of the study. Method of measurement: Psoriasis Severity Index Calculator Software Version 1.7.2.;Measure the percentage of surface area involved in the patient's body. Timepoint: Beginning and end of the study. Method of measurement: Calculated with the formula of the percentage of surface area involved in the patient's body.;Measurement of redness of psoriasis rash. Timepoint: Beginning and end of the study. Method of measurement: Observation and clinical examination.

Secondary Outcome Measures

Name	Time	Method
Measurement of the rash protrusion of psoriasis. Timepoint: Beginning and end of the study. Method of measurement: Observation and clinical examination.;Measuring the extent of scaling of the psoriasis rash. Timepoint: Beginning and end of the study. Method of measurement: Observation and clinical examination.