KCT0005626尚未招募未知
Multicenter, investigator initiated trial, investigating the efficacy and safety of IV-immunoglobulin therapy in elderly patients with diffuse large B cell lymphoma treated with R-CHOP
Chonnam National University Hospital Hwasun Hospital0 个研究点目标入组 158 人开始时间: 待定最近更新:
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 158
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 65(Year) 至 74(Year)（—）
- 性别
- All
入选标准
- •1. Untreated, newly diagnosed with diffuse large B cell lymphoma
- •2. Patients who understand and agree with this study protocol
- •3. Patients who can follow instructions and study protocol
- •4. Age between 65 to 74 years old, male and female
- •5. Ann arbor stage II, III or IV
- •6. Patients who can receive standard R-CHOP chemotherapy
- •7. ECOG PS 0, 1 or 2
排除标准
- •1. Clinically significant uncontrolled systemic disease
- •2. Treatment history of immunotherapy or other chemotherapy for diffuse large B cell lymphoma, except corticosteroid less than 8days
- •3. Ann arbor stage I
- •5. Treatment history of radiotherapy for diffuse large B cell lymphoma
- •6. Central nervous system involvement
- •7. Patients who can not receive R-CHOP therapy
- •8. Known history of infection with HIV
- •9. Absolute neutrophil count < 1,500/mm3
- •10. Platelet count < 75,000/mm3
- •11. Serum creatinine = 2.0 mg/dl or GFR < 50 mL/min
- •12. Serum bilirubin = 2 x upper limit of normal (ULN)
- •13. SGOT/AST or SGPT/ALT = 3 x ULN
- •14. Prior malignancy (or any other malignancy that requires active treatment), except for adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, papillary thyroid carcinoma, or other cancer from which the subject has been disease free for over 5 years or which will not limit survival to less than 5 years
- •15.MUGA scan or TTE Ejection fraction < 45%
- •16. Treatment history with doxorubicin over 200mg/m2
- •17. Concurrent participation in another therapeutic clinical trial
研究者
相似试验
尚未招募
Unknown
Investigator Initiated Trial to Evaluate the Efficacy of FEXUCLUE®40mg(Fexuprazan hydrochloride) in Patients with Iatrogenic Gastric Ulcer After Endoscopic Submucosal DissectioNeoplasmsKCT0008892Presbyterian Medical Center105
已完成
Unknown
A clinical study to assess the safety and efficacy of virtual reality devices that help diagnose Attention-Deficit / Hyperactivity disorder(ADHD)KCT0008403Samsung Changwon Medical Center20
招募中
不适用
The trial to evaluate the safety and efficacy of high dose ambroxol in combination with enzyme replacement therapy in Gaucher disease patientsEndocrine, nutritional and metabolic diseaseKCT0003218Asan Medical Center10
尚未招募
不适用
A study to evaluate the safety of immune cell therapy in early transplant period of hematopoietic stem cell transplant recipientsKCT0004024The Catholic University of Korea, Seoul St. Mary's Hospital32
招募中
4 期
Clinical study of Ulinastatin along with standard of care in comparison to standard of care alone (Pooled historical data) in hospitalised moderate COVID-19 patientsCTRI/2021/08/035593Dr Manjunath B G