The effect of topiroxostat on renal function in type2 diabetes with hyperuricemia
Not Applicable
- Conditions
- type 2 diabetes with serum uric acid levels more than 7 mg/dl and eGFR more than 60 mL/min/1.73m2
- Registration Number
- JPRN-UMIN000022644
- Lead Sponsor
- Osaka City University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1) age more than 80 years or less than 20years 2) The patients who has malignant disease 3) The patients who has heavy heart failer or unstable angina 4) The patients who has heavy hepatic failer (AST or ALT more than 100U) 5) The patients who has renal failure 6) The patients who has past history of gout attack or who is already taking a therapeutic drug of the hyperuricemia 7) The patients who take a medicine which prohibited to taken with topiroxostat 8) Pregnancy planned woman,Pregnant woman,The woman whom I am nursing 9) The patient who has an allergy career to a study drug
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change of measured GFR by topiroxostat (40 mg/day) administration in 7 days
- Secondary Outcome Measures
Name Time Method Change in serum uric acid levels, albuminuria, xanthine oxidoreductase by topiroxostat(40mg/day) administration in 7 days