Comparison of the effect of the calcium citrate supplement with normal calcium diet on metabolic risk factors in recurrent calcium stone formers with hyperoxaluria
Phase 3
Recruiting
- Conditions
- Recurrent calcium stone formers with hyperoxaluria.Calculus of kidneyN20.0
- Registration Number
- IRCT20160206026406N3
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
Recurrent stone former
Hyperoxaluria (24hr Urine Oxalate between 40-80 mg)
Baseline dietary calcium intake less than 800 mg/day
The desire to collaborate in the study
Exclusion Criteria
Enteric or primary hyperoxaluria (24 hours urine oxalate more than 80 mg)
Taking Thiazides or any medicine that has an effect on calcium metabolism
Taking any medicine that has an effect on oxalate metabolism
Taking vitamin B6
Hepatitis, diabetes, thyroid diseases, hyperparathyroidism, immunological diseases, cancers, chronic diarrhea, chronic kidney diseases and urinary tract infection
Pregnancy and lactation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 24hr Urine Oxalate. Timepoint: Before the intervention, 8 weeks after intervention. Method of measurement: Enzymatic method.;Calcium oxalate supersaturation. Timepoint: Before the intervention, 8 weeks after intervention. Method of measurement: Calculation by LITHORISK software.
- Secondary Outcome Measures
Name Time Method rine pH. Timepoint: Before the intervention, 8 weeks after intervention. Method of measurement: pH meter.;24 hour urine oxalate. Timepoint: Before the intervention, 8 weeks after intervention. Method of measurement: Enzymatic method.