Comparison of bioactive glass S53P4 as bone graft substitute and autologous bone graft in the treatment of chronic osteomyelitis and infected non-unions – a comparative retrospective study

• Conditions: M86.6; Other chronic osteomyelitis

• Registration Number: DRKS00014049
• Lead Sponsor: BG Klinikum Duisburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-26
• Study Completion: 2018-07-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 95

Inclusion Criteria

Chronic osteomyelitis and/ or infected non-union
- Filling of the bony defect with either autologous bone graft or bioactive glass S53P4
- Follow-up at a minimum of 12 months

Exclusion Criteria

- Aseptic non-union
- Follow-up < 12 months

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Permanent control of infection during follow-up (date of filling the defect – max. 01/2018)<br>All findings of the consultation hours – independent of this study – are evaluated<br>

Secondary Outcome Measures

Name	Time	Method
- Bony fusion, respectively incorporation of the bioactive glass<br>- Full weight bearing<br>- Complications due to bioactive glass, respectively the extraction of autologous bone graft<br>- Complications<br>All findings of the consultation hours – independent of this study – are evaluated