A Comparative Study of Brain Structure and Amyloid Load in MCI Patients

Withdrawn

• Conditions: Mild Cognitive Impairment

• Registration Number: NCT03773185
• Lead Sponsor: Chinese University of Hong Kong

Brief Summary

Older people with DM are at greater risk of cognitive decline than their counterparts with DM. Cognitive impairment in older people with DM may be associated with non-AD related brain atrophy and white matter disease. The investigators therefore propose to compare DM and non-DM older people with amnesic MCI in brian volumes, white matter disease and amyloid load.

30 older people with aMCI, 30 older people with aMCI and DM, age 65-85 will be recruited. They all will have amyloid PET scan and MRI brain scan.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-11-30
• Study First Submitted QC: 2018-12-11
• Study First Posted: 2018-12-12
• Study Start: 2018-12-15
• Primary Completion: 2020-07-31
• Study Completion: 2020-07-31
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-19
• Last Update Posted: 2021-10-21

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• MCI patients

Exclusion Criteria

• Patients with depression

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Amyloid load	Two years

Trial Locations

Locations (1)

The Chinese University of Hong Kong; 🇭🇰 Hong Kong, Hong Kong