NCT03773185
Withdrawn
N/A
A Comparative Study of Brain Structure and Amyloid Load Between Cognitively Impaired Older People With or Without Diabetes Mellitus
ConditionsMild Cognitive Impairment
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Mild Cognitive Impairment
- Sponsor
- Chinese University of Hong Kong
- Locations
- 1
- Primary Endpoint
- Amyloid load
- Status
- Withdrawn
- Last Updated
- 4 years ago
Overview
Brief Summary
Older people with DM are at greater risk of cognitive decline than their counterparts with DM. Cognitive impairment in older people with DM may be associated with non-AD related brain atrophy and white matter disease. The investigators therefore propose to compare DM and non-DM older people with amnesic MCI in brian volumes, white matter disease and amyloid load.
30 older people with aMCI, 30 older people with aMCI and DM, age 65-85 will be recruited. They all will have amyloid PET scan and MRI brain scan.
Investigators
Timothy Kwok
Professor
Chinese University of Hong Kong
Eligibility Criteria
Inclusion Criteria
- •MCI patients
Exclusion Criteria
- •Patients with depression
Outcomes
Primary Outcomes
Amyloid load
Time Frame: Two years
Study Sites (1)
Loading locations...
Similar Trials
Unknown
N/A
Amyloïd Load in Elderly Population: Effect of Cognitive ReservePlaque, AmyloidCognitive DeficitsNCT02196116University Hospital, Bordeaux120
Recruiting
N/A
Early Diagnosis of SCD Based on RadiogenomicsAlzheimer DiseaseSubjective Cognitive DeclineNeuroimagingGeneNCT04696315XuanwuH 2800
Completed
N/A
The Influence of HDL Function on Cognitive FunctionOlder People With Diabetes MellitusNCT03761719Chinese University of Hong Kong145
Unknown
N/A
Modulation of Cognition and Brain Connectivity by Noninvasive Brain Stimulation in Patients With Mild Cognitive Impairment Due to Alzheimer's DiseaseMild Cognitive ImpairmentNCT04012346Masaryk University20
Recruiting
N/A
Cognitive Decline in ADAlzheimer DiseaseNCT03946930Chinese University of Hong Kong500