Routine Bile Collection for Microbiological Analysis During Cholangiography

Completed

• Conditions: Cholangitis

• Registration Number: NCT01003782
• Lead Sponsor: Hannover Medical School

Brief Summary

Background: Antibiotic treatment of cholangitis often remains insufficient due to inappropriate antibiotic use or bacterial resistance.

Objective: To evaluate the role of routine bile collection during endoscopic retrograde cholangiography (ERC) or percutaneous transhepatic cholangiography (PTC) for microbiological analysis in the antibiotic management of cholangitis and to identify risk factors of microbial growth.

Design: Prospective, observational, diagnostic study.

Setting: Hannover Medical School, Hannover, Germany. Patients and Interventions: Consecutive patients undergoing ERC/PTC for biliary complications after orthotopic liver transplantation , malignancy, primary sclerosing cholangitis, benign strictures and choledocholithiasis.

Main outcome measurements: Microbiological examination of bile samples

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Primary Completion: 2009-02
• Study Completion: 2009-02
• Status Verified: 2009-10
• Study First Submitted: 2009-10-28
• Study First Submitted QC: 2009-10-28
• Last Update Submitted: 2009-10-28
• Study First Posted: 2009-10-29
• Last Update Posted: 2009-10-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• age above 18 years
• written informed consent

Exclusion Criteria

• age under 18 years
• no written informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Hannover Medical school; 🇩🇪 Hannover, Germany