跳至主要内容
临床试验/NCT04345588
NCT04345588Unknown2 期

Comparison of Analgesic Efficacy of Dexamethasone as an Adjuvant in Supraclavicular Block With Intravenous Dexamethasone After Supraclavicular Block in Patients Undergoing Forearm Surgeries

Assiut University0 个研究点目标入组 60 人开始时间: 2021年1月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
2 期
入组人数
60
主要终点
Dexamethasone efficacy as an Adjuvant in Supraclavicular Block

研究概览

简要总结

The use of dexamethasone perineurally along with local anesthetic has been shown to improve the duration of analgesia .

详细描述

Acute postoperative pain can be effectively controlled with the use of peripheral nerve blocks. Use of additives further prolongs the duration of analgesia For upper limb surgeries below shoulder joint, the brachial plexus block using supraclavicular approach introduced by Kulenkampff has gained popularity. Supraclavicular approach to brachial plexus block is useful for procedures done at or below the level of elbow.

This technique involves the deposition of local anesthetic near the brachial plexus approached from immediately above the clavicle. Brachial plexus is formed by ventral rami of C5, C6, C7, C8, and T1 which forms the roots.These then continue distally to form trunks, divisions, cords,and branches Local anesthetics used alone in supraclavicular block provide analgesia for 4-8 h.

The use of dexamethasone perineurally along with local anesthetic has been shown to improve the duration of analgesia. Intravenous dexamethasone is also useful in attenuating the postoperative need for analgesics in different clinical settings even in the absence of any nerve blocks.

Hence, it is logical to compare the duration of analgesia with the use of dexamethasone in the setting of supraclavicular brachial plexus block, dexamethasone given either perineurally or intravenously.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Patients between 18 and 60 years of age
  • Both male and female gender
  • ASA physical status Classes I and II patients
  • Patients posted for upper limb surgery below shoulder.

排除标准

  • Patient refusal
  • Patients with bleeding disorders and those on anticoagulant therapy
  • History of allergy to local anesthetics
  • Infection at the site of block
  • Neuro deficit involving brachial plexus
  • Pregnant women
  • Patients with psychiatric behavior
  • ASA physical status Classes III and IV patients

研究组 & 干预措施

group received dexamethasone perineural

Active Comparator

injection dexamethasone 0.05 mg/kg perineural.

干预措施: Dexamethasone injection (Drug)

group received dexamethasone intravenous

Active Comparator

injection dexamethasone 0.05 mg/kg intravenously.

干预措施: Dexamethasone injection (Drug)

结局指标

主要结局

Dexamethasone efficacy as an Adjuvant in Supraclavicular Block

时间窗: 2 years

we will assess the efficacy of dexamethasone in supraclavicular anaethesia in terms of duration of analgesia and onset of motor and sensory block.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Islam Mohamed Abdel Hamid Ali

Resident doctor

Assiut University

相似试验

Dexamethasone as an Adjuvant in Supraclavicular Block | 临床试验