SUBGLOTTIC INSTILLATION OF FLURBIPROFENE TO PREVENT LARYNGEAL INFLAMMATION FOLLOWING ENDOTRACHEAL INTUBATION: PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED PILOT STUDY - SORE TROATH

FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE0 个研究点目标入组 70 人开始时间: 2020年10月21日最近更新: 2023年9月11日

试验速览

暂无简介。

•¿Patients undergoing 9-12 hours orotracheal intubation for aortocoronary bypass, valve replacement
•¿Plastic surgery in extracorporeal circulation
•¿Patient aged between 50 and 75
•¿Patients in NYHA class I and II
•¿Patients who have given their written consent to the study and treatment of their clinical data for the purpose of the study
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 50
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 20

•Exclusion criteria
•¿Previous upper airway surgery
•¿A positive history of recent acute pathologies or chronic pathologies of the upper airways
•¿Nicotine addiction
•¿Positive history of difficult intubation including objective examination suggestive of difficult
•orotracheal intubation (Mallampati = 3)
•¿Orotracheal intubation with more than two attempts or with the aid of devices (spindles, Airtrag, Fibroscopy)
•¿Nasotracheal intubation
•¿Positive history of gastroesophageal reflux
•¿Patients participating in other experimental trials
•¿Patients who have not given their written consent to participate in the study and have specifically refused the use of their clinical data for the purpose of the study and have not given their consent.

发起方

FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE