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Effect of progesterone and aspirin on refusing uterine artery resistance and pregnancy outcome

Phase 2
Recruiting
Conditions
Effect of Progesterone and Aspirin on reducing uterine artery resistance and pregnancy outcome.
Aspirin, Progesterone, uterine artery resistance
Registration Number
IRCT20160308026962N5
Lead Sponsor
Oroumia University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
200
Inclusion Criteria

The patient is in the first 3 months of pregnancy.
The women who do not have history of abortion.
The women who are not emergency patients.
The women who are not pregnant with multiples.

Exclusion Criteria

Having a body mass index greater than 30 kg/m2.
Having high blood pressure
Disagreeing to participate in the study
Taking Aspirin in the last week
Having Aspirin sensitivity
Having Progesterone sensitivity
Taking Progesterone in the last week
Having a uterine abnormality
Having a history of gastrointestinal disease

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
terine artery resistance. Timepoint: At the beginning of the study, patients undergoing color Doppler vaginal ultrasounds of the uterine arteries will be placed by a single perinatologist to determine the average PI and RI of the uterine arteries, then they will be given aspirin and progesterone for 2 weeks. At the end of two weeks, the cervical artery vaginal ultrasound will be performed again. The mean changes in the PI and RI of the uterine arteries after taking the medication will be evaluated. Method of measurement: Checklist before and after intervention.
Secondary Outcome Measures
NameTimeMethod
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